The group released several tape singles and two albums primarily on Dan the Automator's experimental hip-hop label 75 Ark before being signed by Warp Records in 2000. Their releases were met with mixed reviews from the mainstream music and underground hip-hop press alike, although they are noted for their inventiveness and the experimental electronic productions contributed by all members. They were frequently compared to other rappers with unorthodox lyrics, such as Kool Keith, MF Doom and Aesop Rock. In 2001, they opened for Radiohead during the European leg of their Amnesiac tour and subsequently toured with DJ Shadow.
The group disbanded due to creative differences in August 2002, with Beans pursuing a solo career while High Priest and M. Sayyid formed Airborn Audio, which released a single album, Good Fortune, on Ninja Tune in 2005, and toured with The Faint and Bright Eyes. All three members have pursued solo projects since the group's breakup.
Antipop completed their third album before they broke up, released in February 2003 as Antipop Consortium vs. Matthew Shipp.
They reunited in 2007. In an August 2007 interview, the four members stated that they reunited with the intention of touring and releasing a new record.
They played a reunion show at the Knitting Factory of New York City in March 2008 and formed part of the support for Public Enemy on the It Takes A Nation Of Millions To Hold Us Back Don't Look Back British tour in May 2008. They have played at the 2009 ATP VS the Fans festival in Minehead, UK, followed by the Incubate Festival in Tilburg, Netherlands the following week.
After releasing their reunion album Fluorescent Black on Big Dada Records in 2009, the group has been touring steadily. Playing shows in Pontiac, Michigan; Futuresonic at Urbis in Manchester, UK (May 14, 2009), as well as appearing at the South By Southwest Music Festival in Austin, Texas in 2010. After playing at SXSW they played at the Incubate in Tilburg, Netherlands in September 2009.
In 2011 Antipop Consortium released "Knives From Heaven" featuring Matthew Shipp and William Parker